Greenville Hotel's Keeping Southern Charm In Business Greenville is home to some of the Upstate's largest and most exciting industries, including Fluor, Windstream, GE, Michelin and BMW. This Greenville, SC hotel's location is close to the hustle and bustle of Main Street and minutes from I-385 and I-85, as well as within walking distance of everything from the Bi-Lo Center to the endless downtown restaurants and shops. Business travelers enjoy the convenience of free wired and wireless Internet access in all the hotel's rooms. With Greenville, SC businesses from Michelin North America to Brains On Fire at your doorstep, you'll have convenient access and a quick commute to meetings. Visitors to Artisphere, Fall for Greenville or the many other seasonal festivals enjoy the hotel's downtown Greenville, SC address. A moment beneath the lighted trees of Main Street will convince you why Great Places in America named this a Top 10 Main Street. The hotel is ideally situated for students and parents touring Furman, Bob Jones or the Governor's School. A convenient location is only a part of our draw. The sparkling, outdoor pool or the Fitness Center can energize you, and you can start each day with fresh coffee and a hot meal from the free Express Start Breakfast Bar. We continue to help you save by providing complimentary parking. History, innovation and industry are at your doorstep at the Holiday Inn Express® & Suites Greenville Downtown.